Download e-book for iPad: Antineoplastic Drugs: Organic Syntheses by Daniel Lednicer

By Daniel Lednicer

ISBN-10: 1118892542

ISBN-13: 9781118892541

The prior decade has obvious an important bring up of study aimed toward learning new medicinal drugs for treating melanoma, and the expanding variety of new antineoplastic medications authorized through regulatory businesses displays this. before, info at the synthesis of those more moderen brokers were scattered in quite a few journals and in US and eu patents. This well timed quantity offers with the natural chemistry all for the synthesis of the brokers discovered inside of antineoplastic medicines, together with descriptions of the unreal schemes for the instruction of over two hundred compounds which have been granted non-proprietary names. Compounds are accumulated in chapters in accordance with the mechanism of motion instead of on their chemical constructions. each one person bankruptcy is preceded by means of a quick description of that mechanism and comprises specified circulation charts of the education of these compounds followed by means of discussions of the natural chemistry desirous about every one step. the 1st half this quantity is devoted to the syntheses of demonstrated chemotherapy medicinal drugs. Kinase inhibitors occupy the subsequent chapters with the most important unmarried bankruptcy facing the fifty compounds that inhibit tyrosine kinase. This classification stands proud on account that over twenty compounds during this workforce were licensed for treating sufferers; a unprecedented song list in comparison to the other type of healing brokers. Antineoplastic medications: natural Syntheses is written to attract natural and medicinal chemists in and academia. it really is valuable to these composing supply proposals for NCI and comparable enterprises. The ebook is offered to complex undergraduates in addition to graduates and researchers in addition to people with a radical seize of natural chemistry.

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Antineoplastic Drugs: Organic Syntheses by Daniel Lednicer

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